Postdoctoral Research Fellow
The Gleeson lab is continually seeking to recruit the most talented and dedicated molecular neuroscientists to work on challenging, exciting and fun projects int he area of neurodevelopment. The position offers an amazing opportunity to continue training in neuroscience with an emphasis on genetics and high-throughput approaches. Our lab works with an extensive cohort of nearly 2000 families with inherited neurological disease in order to understand the genetic requirements of human brain development. Fellows work on independent disease entities as part of a larger network of researchers involved in these studies, and fully supported by a dedicated team of staff scientists. Postdoctoral fellows receive training in the area of human phenotying, pedigree analysis, next generation sequencing, computational analysis, and genomics. Most projects involve aspects of advanced cellular biology, induced pluripotent stem cell modeling, zebrafish analysis, primary neuronal culture, mouse models, advanced high-resolution microscopy, and proteomics. Because we are in a highly-interactive and collaborative environment as part of the La Jolla biomedical research community, fellows frequently spend time in collaborating labs to gain additional expertise. With these diverse training opportunities, many of our trainees have gone on to competitive positions at top research institutions. Experience in cellular biology, molcular biology or genetics is a plus. Please send CV and list of three references to Joseph G. Gleeson, Howard Hughes Medical Institute, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0665 or contact firstname.lastname@example.org.
Specialist or Postdoctoral Scholar in Bioinformatics
Next-generation sequencing has helped uncover important roles for genes in human disease, but many important questions remain that will require novel computational methodology. A research position in the Institute of Genomic Medicine at the University of California San Diego School of Medicine is available in the area of statistical genetics for a highly motivated individual with an excellent record of research productivity. The candidate will integrate into an existing human genetics team generating and analyzing DNA or RNA sequence data from a variety of application and help develop computational systems for analysis. Specific work will focus on the analysis of patterns of genetic variants using whole exome, whole genome and transcriptome sequencing datasets to understand human disease and genetic variation. The successful candidate will have excellent computational skills including extensive experience with PERL/Python/Java/C++, UNIX/LINUX, R/MATLAB programs as well as experience in gene expression, genetic variation analysis, integration with the Human Genome Browser and genetic databases. Experience in molecular biology and high-throughput approaches are a plus. Submit a curriculum vitae, letter describing research experiences and career goals along two references to Joseph G. Gleeson, Howard Hughes Medical Institute, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0665 or contact email@example.com.